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William "Bill" Wold, Ph.D.: 1944-2021

06/21/2021

William 鈥淏ill鈥� Sydney Martin Wold, Ph.D., professor and former department chair in molecular microbiology and immunology at 老司机福利网 School of Medicine, died June 14, 2021. He was 77.

Wold joined the University in 1973 and was scheduled to retire in August. His research focused on treatments and potential cures for cancer.

He was born Feb. 12, 1944, in Manitoba, Canada. Wold attended the University of Manitoba in Winnipeg for his bachelor鈥檚 degree. He also earned master鈥檚 and doctoral degrees in microbiology from the University.

After receiving his Ph.D. in 1973, Wold came to 老司机福利网 as a post-doctoral fellow in the Institute for Molecular Virology under Maurice Green, Ph.D.

He noted in 2003 that there is 鈥渁 long tradition of adenovirus research at Saint Louis University School of Medicine dating back to the 1950s, and it can be argued that SLU is the birthplace of adenovirus molecular virology.鈥�

Wold worked his way up from instructor to professor to chairman of what became, under his leadership, the Department of Molecular Microbiology and Immunology.

Building on a tradition of adenovirus molecular virology at SLU, Wold鈥檚 laboratory participated in the discovery of a new class of viral proteins that orchestrate the life and death of adenovirus-infected human cells.

Wold studied the molecular aspects of human adenovirus replication for four decades. Adenoviruses are one of the premier model systems to study the molecular and cellular biology of human cells.

In other research, Wold鈥檚 lab developed the Syrian hamster as a unique animal model to study the pathogenesis of human adenoviruses and to evaluate the efficacy of drugs to treat adenovirus infections.

Duane Grandgenett, Ph.D., professor of molecular microbiology and immunology, said he first met Wold in 1974 when he arrived at SLU.

鈥淭o me, one of Bill鈥檚 most outstanding traits was to always try his best - from taking care of his family, to doing his science, to especially helping students, postdoctoral fellows and other faculty members, to being a sport man particularly as a long-distance runner and for sure, as an outstanding chairman,鈥� Grandgenett said. 鈥淗e made a big difference with his many contributions to humanity.鈥�

Wold was named a Fellow of the Academy of Science of St. Louis in 2002. He also was a member of the American Society for Microbiology, American Society for Virology and the American Society for the Advancement of Science.

Wold is survived by his wife of 53 years, Susan (Lees) Wold; children Lora Wold (Robb Hellwig), Guy Wold, Jessica Wold (Andreas Bieri) and Jonathan Wold; grandchildren Madeline Hellwig, Sydney Hellwig, Niko Wold and Syrsha Wold. He was preceded in death by parents Roy and Nellie Wold and brother Larry.

Memorial services are being planned for August, his anticipated retirement date from SLU.