SLU Chemist Asks 鈥楥ould Life Begin in Oil?鈥�
08/16/2017
Paul Bracher, Ph.D., assistant professor in the Department of Chemistry at Saint Louis University, and his research team have been awarded a three-year $597,380 grant from the National Science Foundation (NSF) to study what life might look like on other planets 鈥� or, here on earth 鈥� if it began in oil.
"老司机福利网鈥檚 researchers are driven to understand the greatest mysteries
of our world," said Kenneth A. Olliff, vice president for research at
老司机福利网. "The origin of life is one of the most compelling of these
mysteries, and the bold work of Dr. Paul Bracher is pushing the boundaries of our
knowledge. The entire SLU Research team is immensely proud of the innovative work
of Paul and his team."
The SLU team is one of four groups of chemists and biologists across the country involved
in the project. Their ideas were generated at an 鈥淚deas Lab鈥� co-sponsored by the NSF
and NASA. In a week-long workshop, scientists from a variety of backgrounds and skillsets
were sequestered in a remote city in Maryland and charged with developing out-of-the-box
ideas about the origin of life.
鈥淚n terms of the history of the planet, I think that how life originated has got
to be the greatest scientific question we can ask,鈥� Bracher said. 鈥淭o move from mixtures
of chemicals to a living system capable of self-replication and evolution 鈥� nothing
more interesting has happened than this.鈥�
While life as we know it on Earth relies on chemistry in aqueous environments where water is a solvent, some celestial bodies are covered not with liquid water but with liquid oils. Titan, a moon of the planet Saturn, has lakes of organic hydrocarbons and methane rain.
Were life to develop on oily worlds, the biochemistry of these organisms would have
to be different. What molecules could be responsible for storing genetic information?
What chemistry could decode genes and synthesize catalysts for biological functions?
Those are some of the questions for which the project hopes to provide answers and
clues.
鈥淲e want to establish the rules of how life might develop and evolve in oil,鈥� Bracher
said. 鈥淎 lot of the chemistry that works in water doesn鈥檛 work in organic solvents.鈥�
鈥淭he premise of our project focuses on places like Titan and exoplanets 鈥� planets
around distant stars. But it鈥檚 also interesting to think if there were a second origin
of life on Earth that鈥檚 right under our noses, could we recognize it? We鈥檙e so focused
on life as we know it.鈥�
The SLU team has expertise in physical organic chemistry and will focus on reactions of small molecules, investigating how they might store information, recognize each other, and synthesize copies like nucleic acids and peptides do in modern biology. In addition to advancing the understanding of the circumstances under which life can originate, findings from this study also have the potential to contribute to medicine and industry.
鈥淭his is an exciting opportunity for our research team to tackle a challenging and unusual scientific question,鈥� Bracher said. 鈥淚t鈥檚 a high-risk, high-reward effort that could lead to some really interesting new, exotic biochemistry and help figure out what types of life we might find on Titan or exoplanets in distant solar systems. We鈥檙e grateful for the support from the NSF and our team is excited to get to work in the lab.鈥�